What is Muscle Hypertrophy?

By Tafity — 3/25/2026

What is Muscle Hypertrophy?
**Muscle hypertrophy** is the increase in the size of muscle cells (fibers), which leads to an overall increase in muscle volume. This process is an adaptive response of the body to physical stress, mainly through strength training. There are two main types of hypertrophy: **myofibrillar hypertrophy** and **sarcoplasmic hypertrophy**. Myofibrillar hypertrophy involves an increase in the number and size of **myofibrils**, which are the contractile units within muscle fibers. This type is more associated with an increase in **muscle strength**. Sarcoplasmic hypertrophy, on the other hand, refers to an increase in the volume of **sarcoplasm**, which is the fluid inside the muscle cell, containing glycogen, minerals, and other substances. This type contributes to an increase in **muscle size** (volume). The stimulus for hypertrophy occurs when muscles are subjected to workloads that cause microscopic damage to muscle fibers. During the recovery period, the body repairs these fibers and makes them stronger and larger so they can better handle similar stressors in the future. Adequate nutrition, especially **protein** intake, and **rest** are crucial for optimizing this repair and growth process. To achieve hypertrophy, a consistent training program is necessary, including progressive overload, adequate rest, and a nutrient-rich diet. It's important to note that genetics also plays a role in an individual's ability to gain muscle mass. For those seeking strength and size, combining different types of training can be beneficial, as well as for those who have, for example, **joint hypermobility** and need to train safely to gain strength.